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Generating evidence and developing deployable AI technologies for global health and humanitarian response

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Programs

Generating evidence and developing deployable AI technologies for global health and humanitarian response.

LiGHT Map

Where we work

Where we work

We build AI systems that work where they are needed most by prioritizing openness, real-world validation, and local relevance.

This means collaborating with users at every stage: from defining use cases to integrating tools into clinical workflows, while ensuring models are trained on high-quality, contextually grounded data. 

We emphasize open-source development, ethical governance, and capacity building, designing systems that can operate under real constraints such as limited data, connectivity, and infrastructure, and that can be sustained and owned locally.  

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Contextualized Models
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Real world
clinical studies
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Clinically-centered AI applications
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Privacy-preserving distributed learning

Clinical Trials

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IMCI-Plus

An interdisciplinary, Pan-African-European Union research initiative which aims to improve the management of childhood pneumonia by pioneering the use of point-of-care lung ultrasound in everyday clinical practice, and policy.

Website
CADLUS4TB Icon.png

CADLUS4TB

An EDCTP3-funded research project bringing together partners across Africa and Europe to improve tuberculosis diagnosis through AI-driven computer-assisted lung ultrasound in Benin, Mali and South Africa.

Website
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MOOVE

MOOVE (Massive Open Online Validation and Evaluation) is a global, expert-led initiative that enables clinicians, humanitarian actors, and local experts to evaluate AI models against the realities of their own settings. Rather than a single study or platform, MOOVE is a progressive clinical validation pathway: partners begin with hypMOOVE, where experts evaluate AI using hypothetical clinical scenarios; advance to silentMOOVE and retroMOOVE, where AI is evaluated on real patient data without influencing clinical decisions; and, when sufficient evidence has been established, progress to trueMOOVE, where AI is evaluated in randomized controlled trials. Across all stages, MOOVE generates expert preference data, context-adapted models, locally owned datasets, and research-grade publications. The MOOVE programme currently comprises MOOVE Africa (Tanzania, Rwanda, Kenya, Malawi, and Ethiopia), MEDUSE (Switzerland), and MOOVE India, advancing AI evaluation and clinical validation across diverse healthcare settings.

Website

Open Foundation Models

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Meditron

MeditronFO (Fully Open) is the first fully open medical specialist LLM, and outperforms Medgemma on open ended clinical evaluations.

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ultr-AI

Multimodal foundation models integrating text, images, signals, and clinical data.

AI Architectures

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MoBayes

MoBayes constructs an explicit clinical knowledge base, then iteratively gathers evidence through LLM-parsed patient dialogue and updates beliefs with Bayesian inference — outperforming much larger standalone LLM doctors at a fraction of the cost. The LLM is confined to parsing and verbalization, while a deterministic Bayesian module handles posterior tracking, question selection, and calibrated abstention.

Publication
MultiModN Icon.png

MultiModN

MultiModN explores modular neural architectures for multimodal, multi-task learning, with a focus on interpretable fusion across heterogeneous data sources. The project introduces a flexible approach to combining modalities sequentially, supporting robust prediction even when some information is missing not at random.

Website

Open Infrastructure

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DISCO

DIStributed COllaborative Learning, Train AI Models Together. Keep Data Private. Build and train AI models without sharing any data. Machine Learning directly in your browser.

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Talk2YourData

Talk2yourdata enables natural language querying of DHIS2 health data.

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mmore

Massive Multimodal Open RAG & Extraction (mmore) pipeline to personalize LLMs with a diverse corpus of multimodal inputs.

Clinical Decision

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OneScope

A multi-parameter smart stethoscope.

Website
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Antibiogo

​A mobile application for the automated assessment of antibiograms (with MSF).

Website

Communities of Practice

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AI POCUS

An international collaborative network that brings together clinicians, researchers, developers, implementers, policymakers, donors, industry, and health organizations to accelerate the safe, equitable, and evidence-based adoption of AI-enabled point-of-care ultrasound (AI-POCUS) in low- and middle-income countries (LMICs).

Download models
MOOVE Icon 2.png

MOOVE

MOOVE is a global, expert-led platform that enables clinicians and humanitarian professionals to rigorously evaluate AI systems against real-world local healthcare contexts, generating trusted evidence on safety, quality, and contextual relevance. By combining community governance, data sovereignty, and continuous validation, MOOVE helps adapt AI models to the populations and settings they are intended to serve, particularly in underserved and low-resource environments.

Website
  • Meditron Icon 2

    MoBaye

    MoBayes constructs an explicit clinical knowledge base, then iteratively gathers evidence through LLM-parsed patient dialogue and updates beliefs with Bayesian inference — outperforming much larger standalone LLM doctors at a fraction of the cost. The LLM is confined to parsing and verbalization, while a deterministic Bayesian module handles posterior tracking, question selection, and calibrated abstention.

    Read More
    No Logo

    MultiModN

    MultiModN explores modular neural architectures for multimodal, multi-task learning, with a focus on interpretable fusion across heterogeneous data sources.
    The project introduces a flexible approach to combining modalities sequentially, supporting robust prediction even when some information is missing not at random.

    Read More
    No Logo

    MoDN

    Modular clinical prediction models that operate with incomplete patient information and fragmented healthcare records. 

  • OneScope Icon

    OneScope

    A multi-parameter smart stethoscope.

    Read More
    Antibiogo Icon

    Antibiogo

    ​A mobile application for the automated assessment of  antibiograms (with MSF).

    Read More
  • IMCI Plus Icon

    IMCI-Plus

    An interdisciplinary, Pan-African-European Union research initiative which aims to improve the management of childhood pneumonia by pioneering the use of point-of-care lung ultrasound in everyday clinical practice, and policy.

    Website
    CADLUS4TB Icon

    CAD LUS4TB

    An EDCTP3-funded research project bringing together partners across Africa and Europe to improve tuberculosis diagnosis through AI-driven computer-assisted lung ultrasound in Benin, Mali and South Africa.

    Website
    MOOVE Icon 2

    MOOVE

    MOOVE (Massive Open Online Validation and Evaluation) is a global, expert-led initiative that enables clinicians, humanitarian actors, and local experts to evaluate AI models against the realities of their own settings. Rather than a single study or platform, MOOVE is a progressive clinical validation pathway: partners begin with hypMOOVE, where experts evaluate AI using hypothetical clinical scenarios; advance to silentMOOVE and retroMOOVE, where AI is evaluated on real patient data without influencing clinical decisions; and, when sufficient evidence has been established, progress to trueMOOVE, where AI is evaluated in randomized controlled trials. Across all stages, MOOVE generates expert preference data, context-adapted models, locally owned datasets, and research-grade publications.

     

    The MOOVE programme currently comprises MOOVE Africa (Tanzania, Rwanda, Kenya, Malawi, and Ethiopia), MEDUSE (Switzerland), and MOOVE India, advancing AI evaluation and clinical validation across diverse healthcare settings.

    Website
  • Meditron Icon 2

    Meditron

    MeditronFO (Fully Open) is the first fully open medical specialist LLM, and outperforms Medgemma on open ended clinical evaluations.

    UltraAI Icon

    ultra-AI 

    Multimodal foundation models integrating text, images, signals, and clinical data. 

  • MoBayes

    MoBayes

    MoBayes constructs an explicit clinical knowledge base, then iteratively gathers evidence through LLM-parsed patient dialogue and updates beliefs with Bayesian inference — outperforming much larger standalone LLM doctors at a fraction of the cost. The LLM is confined to parsing and verbalization, while a deterministic Bayesian module handles posterior tracking, question selection, and calibrated abstention.

    Publication
    MultiModN Icon

    MultiModN

    MultiModN explores modular neural architectures for multimodal, multi-task learning, with a focus on interpretable fusion across heterogeneous data sources. The project introduces a flexible approach to combining modalities sequentially, supporting robust prediction even when some information is missing not at random.

    Code
  • DISCO Icon

    DISCO

    DIStributed COllaborative Learning, Train AI Models Together. Keep Data Private. Build and train AI models without sharing any data. Machine Learning directly in your browser.

    mmore Icon

    mmore

    Massive Multimodal Open RAG & Extraction (mmore) pipeline to personalize LLMs with a diverse corpus of multimodal inputs.

    Talk2YourData Icon

    Talk2YourData

    Talk2yourdata enables natural language querying of DHIS2 health data.

    Code
  • OneScope Icon

    OneScope

    A multi-parameter smart stethoscope.

    Website
    Antibiogo Icon

    Antibiogo

    ​A mobile application for the automated assessment of  antibiograms (with MSF).

    Website
  • AI Pocus Icon

    AI POCUS 

    An international collaborative network that brings together clinicians, researchers, developers, implementers, policymakers, donors, industry, and health organizations to accelerate the safe, equitable, and evidence-based adoption of AI-enabled point-of-care ultrasound (AI-POCUS) in low- and middle-income countries (LMICs).

    Download models
    MOOVE Icon 2

    MOOVE

    MOOVE is a global, expert-led platform that enables clinicians and humanitarian professionals to rigorously evaluate AI systems against real-world local healthcare contexts, generating trusted evidence on safety, quality, and contextual relevance. By combining community governance, data sovereignty, and continuous validation, MOOVE helps adapt AI models to the populations and settings they are intended to serve, particularly in underserved and low-resource environments.

    Website
  • Meditron Icon 2

    MoBaye

    MoBayes constructs an explicit clinical knowledge base, then iteratively gathers evidence through LLM-parsed patient dialogue and updates beliefs with Bayesian inference — outperforming much larger standalone LLM doctors at a fraction of the cost. The LLM is confined to parsing and verbalization, while a deterministic Bayesian module handles posterior tracking, question selection, and calibrated abstention.

    Read More
    No Logo

    MultiModN

    MultiModN explores modular neural architectures for multimodal, multi-task learning, with a focus on interpretable fusion across heterogeneous data sources.
    The project introduces a flexible approach to combining modalities sequentially, supporting robust prediction even when some information is missing not at random.

    Read More
    No Logo

    MoDN

    Modular clinical prediction models that operate with incomplete patient information and fragmented healthcare records. 

  • OneScope Icon

    OneScope

    A multi-parameter smart stethoscope.

    Read More
    Antibiogo Icon

    Antibiogo

    ​A mobile application for the automated assessment of  antibiograms (with MSF).

    Read More
  • IMCI Plus Icon

    IMCI-Plus

    An interdisciplinary, Pan-African-European Union research initiative which aims to improve the management of childhood pneumonia by pioneering the use of point-of-care lung ultrasound in everyday clinical practice, and policy.

    Website
    CADLUS4TB Icon

    CAD LUS4TB

    An EDCTP3-funded research project bringing together partners across Africa and Europe to improve tuberculosis diagnosis through AI-driven computer-assisted lung ultrasound in Benin, Mali and South Africa.

    Website
    MOOVE Icon 2

    MOOVE

    MOOVE (Massive Open Online Validation and Evaluation) is a global, expert-led initiative that enables clinicians, humanitarian actors, and local experts to evaluate AI models against the realities of their own settings. Rather than a single study or platform, MOOVE is a progressive clinical validation pathway: partners begin with hypMOOVE, where experts evaluate AI using hypothetical clinical scenarios; advance to silentMOOVE and retroMOOVE, where AI is evaluated on real patient data without influencing clinical decisions; and, when sufficient evidence has been established, progress to trueMOOVE, where AI is evaluated in randomized controlled trials. Across all stages, MOOVE generates expert preference data, context-adapted models, locally owned datasets, and research-grade publications.

     

    The MOOVE programme currently comprises MOOVE Africa (Tanzania, Rwanda, Kenya, Malawi, and Ethiopia), MEDUSE (Switzerland), and MOOVE India, advancing AI evaluation and clinical validation across diverse healthcare settings.

    Website
  • Meditron Icon 2

    Meditron

    MeditronFO (Fully Open) is the first fully open medical specialist LLM, and outperforms Medgemma on open ended clinical evaluations.

    Website
    UltraAI Icon

    ultra-AI

    Multimodal foundation models integrating text, images, signals, and clinical data. 

  • MoBayes

    MoBayes

    MoBayes constructs an explicit clinical knowledge base, then iteratively gathers evidence through LLM-parsed patient dialogue and updates beliefs with Bayesian inference — outperforming much larger standalone LLM doctors at a fraction of the cost. The LLM is confined to parsing and verbalization, while a deterministic Bayesian module handles posterior tracking, question selection, and calibrated abstention.

    Publication
    MultiModN Icon

    MultiModN

    MultiModN explores modular neural architectures for multimodal, multi-task learning, with a focus on interpretable fusion across heterogeneous data sources. The project introduces a flexible approach to combining modalities sequentially, supporting robust prediction even when some information is missing not at random.

    Code
  • DISCO Icon

    DISCO

    DIStributed COllaborative Learning, Train AI Models Together. Keep Data Private. Build and train AI models without sharing any data. Machine Learning directly in your browser.

    Publication
    mmore Icon

    mmore

    Massive Multimodal Open RAG & Extraction (mmore) pipeline to personalize LLMs with a diverse corpus of multimodal inputs.

    Publication